# Readme 

Data and code to reproduce the manuscript [Evo 2′s Perception of Single Nucleotide Substitutions in the Genes of Two Plant Model Organisms](https://www.biorxiv.org/content/10.64898/2026.07.01.729829).

- `manuscript.zip` stores the code reproducing the full workflow, from downloading the sequence data from Ensembl, to reproducing the full manuscript as published on Biorxiv.

- `sns-evo2-sequences.tar` stores the sequences with single nucleotide substitutions in fasta format.

- `sns-evo2-likelihoods.tar.gz` stores the likelihoods produced by Evo 2 7b when analyzing the substituted sequences. This file is made available for those wanting to reproduce the analysis presented in the manuscript without running Evo 2 themeselves, skipping the most computationally intense step.